How to apply in “Who is hiring?” for remote job?

Hi all,

I am looking for my first remote job and I am looking at "Who is hiring?" posts.

There are some jobs following this pattern (1) for job applicants:

  -To apply, please submit your resume to: <email>

  -Feel free to contact me directly at <email> with your resume.

  -Get in touch: <company url that can you apply>

and some other with that pattern (2):

  -we would love to hear from you. Email us

  -if you want to learn more, reach out to us <email>

  -Contact me (founder) directly: <email>

  -Email available in profile

  -Please drop us an e-mail at <email> if you’re interested.

For the (1) approach it is straight forward you either send your resume with email or via company link. For the (2) approach what I supposed to do? What is the best approach? Send directly the resume? send an introductory email? Ask some questions if you are not sure about the job description?

Thank you