Lithium

(targethealth.com)

19 points | by lelf 1277 days ago

1 comments

  • JSeymourATL 1275 days ago
    One could make a case that lithium is the Cinderella of psychotropic medications, neglected and ill used. Reported by an Australian psychiatrist, John Cade, in 1949 to be an effective treatment for bipolar disorder (it was approved as a drug by the Food and Drug Administration in 1970) its efficacy in mood disorders and suicide prevention has been documented as well as or better than virtually any other psychotropic medication. But it retains a grim and undeserved reputation, perhaps because it was originally associated in the public mind with serious mental illness and because, like many medications, lithium can have serious side effects if not monitored properly. As a psychiatrist, I can tell you that because of its stigma, lithium as a medication is a hard sell to patients with serious mood disorders who could clearly benefit from treatment. But there are undoubtedly other reasons for its neglect. Pharmaceutical companies have nothing to gain from this cheap, ubiquitous element.

    > https://www.nytimes.com/2014/09/14/opinion/sunday/should-we-...

    • dillondoyle 1275 days ago
      Really? I was under the impression that we have largely moved on because of better medicine.

      My doc explained that Lithium has some pretty serious long term problems for many patients while for instance if you can tolerate the titration Lamotrigine has very few side effects. Was also told Lamotrigine was more effective at least for my needs.

      • rozab 1275 days ago
        The 'better medicine' we have nowadays is less toxic but barely more effective than placebo (I would argue they ARE just placebo, with trials being invalidated by broken blinds).
        • dillondoyle 1274 days ago
          It has been a game changer for me. Maybe placebo but it's been a long time and truly very very big difference
    • BigBubbleButt 1275 days ago
      How often would you say lithium helps and how often would you say it was a net-negative when considering the side effects of patients you've treated?